Mayim Bialik shares ‘terrible’ reason why she and Neil Patrick Harris are no longer friends

Friends may come and go in your life, but the memories stay forever.

Mayim Bialik has revealed how her friendship with Neil Patrick Harris disintegrated back in the 1990s.

The “Big Bang Theory” actress and “Jeopardy!” host, 45, confessed that she is not a fan of musicals during a chat with James Corden on “The Late Late Show” on Tuesday. But she shared a “terrible story” about the time she was a teen and saw a 1997 production of the Jonathan Larson-penned show “Rent,” in which her then-friend Harris, now 48, played filmmaker Mark Cohen. The audience gave him a big round of applause for his performance — but Bialik wasn’t having it.

“I mean, this was a long time ago … But when your friend is in the play and then everybody is clapping at the end, and you say to your boyfriend next to you, ‘I don’t want to stand for this’ …

“And then you look up and Neil Patrick Harris is looking right at you — it’s a bad day.”

She did clarify that post-“Doogie Howser” Harris was “fantastic,” but she still didn’t feel compelled to pump him up.

“I mean, he is amazing, but I just wasn’t into the [idea of], ‘Let’s give a standing ovation.’ It wasn’t my thing,” she continued. Then things got much worse.

“But that’s the time when you don’t say it out loud, because Neil was reading my lips, and when I went backstage to say hi to him … he said, I kid you not, ‘Why did you say you weren’t going to stand up?’

“He read my lips,” she said. “I did not have a good answer. It was terrible. It was bad.”

Luckily, Harris has apparently forgiven her and tried to smooth things over.

“We didn’t speak for a long time. [Harris] says that he forgave me and he sent me flowers when he heard that I’m still carrying this terrible [guilt] — I mean, I felt terrible,” the “Call Me Kat” actress continued. “It just wasn’t my thing.”